April 8, 2024 – Vizgen, Inc. the life science company dedicated to improving human health by visualizing single-cell spatial genomics information, unveils the MERSCOPE® Ultra Platform and MERFISH 2.0 chemistry. These powerful tools are uniquely suited to supporting basic and translational research and will be commercially available in the second half of the year.

With 3x increased imaging area and 2x speed, coupled with enhanced MERFISH sensitivity, MERSCOPE Ultra will offer greater sample flexibility and throughput, accelerating both human and translational research.

The MERSCOPE Ultra Platform is a powerful new high plex in situ spatial multiomic analysis system. The MERSCOPE Ultra features the optimum combined capabilities of imaging area and throughput in a spatial transcriptomics imaging platform. The platform is capable of processing 3 cm2 of tissue on a single slide and acquires images at more than double the speed of the MERSCOPE Platform. Engineered for high-performance and optimized for throughput, MERSCOPE Ultra provides researchers with an industry-leading combination of imageable area, speed, and data quality to accelerate discovery and maximize the biology measured from every sample. Further, the system is the only spatial platform to offer two different size flow cells enabling users to adjust reagent consumption based on area imaged.

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With the launch this week of its new Tapestri platform, single-cell omics firm Mission Bio is looking to make further inroads into the clinical trial and drug development businesses.

The new system adds protein measurements to the company's traditional focus on single-cell DNA sequencing, allowing researchers to make DNA and protein measurements in a single experiment and in single cells.

The system uses BioLegend's TotalSeq antibodies, which are conjugated to oligonucleotides, allowing them to be read out via single-cell sequencing. The current version of the Tapestri platform is intended for analysis of cell surface proteins, which enables researchers to identify cell type and subtype, generating data analogous to that provided by flow cytometry.