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CELENA® X High Content Imaging System

The CELENA® X High Content Imaging System is an integrated imaging system designed for rapid, high content image acquisition and analysis. Customizable imaging protocols, image-based and laser autofocusing modules, and a motorized XYZ stage simplify well plate imaging and slide scanning. The integrated CELENA® X Cell Analyzer software processes images and data for quantitative analysis. Analysis pipelines can be put together and reused to identify cellular or subcellular objects, process images for optimal data collection, and make various measurements.

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Features

Automated high content image acquisition and analysis for drug discovery and cell biology

The CELENA® X is as flexible as it is powerful, with interchangeable objectives and filter cubes to accommodate a wide range of fixed and live cell imaging applications.

Simple High Content Imaging for Quantitative Image-base Analysis

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FULLY AUTOMATED PLATE AND SLIDE IMAGING

FULLY AUTOMATED PLATE AND SLIDE IMAGING

  • Automated vessel handling and scanning
  • Motorized XYZ stage, filter cube stage, and objective turret
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LASER AUTOFOCUS

LASER AUTOFOCUS

  • Rapid and reproducible focusing 
  • Minimized phototoxicity and photobleaching
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LIVE CELL ASSAY SUPPORT

LIVE CELL ASSAY SUPPORT

Onstage incubation system for a variety of experiments in physiological and non-physiological conditions

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FOUR IMAGING MODES

FOUR IMAGING MODES

Fluorescence imaging in four channels, brightfield, color brightfield, and phase contrast imaging

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POWERFUL, EASY-TO-USE USER INTERFACE

POWERFUL, EASY-TO-USE USER INTERFACE

  • Simple setup of imaging protocols 
  • Seamless integration of imaging and data analysis processes
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CUSTOMIZABLE HIGH CONTENT ANALYSIS

CUSTOMIZABLE HIGH CONTENT ANALYSIS

  • Create and customize image analysis projects 
  • Quantitatively analyze multiple image-based phenotypes

Create your own imaging and analysis workflows with the CELENA® X

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Abundant Applications

The CELENA ® X Cell Analyzer software is incredibly powerful and its ability to batch process makes it ideal for high content analysis.
The powerful and flexible software allows for the creation and customization of workflows that can be used for the simplest fixed cell assays to more complicated, time-lapse live cell assays.

Apoptosis
Autophagy
Cell cycle
Cell counting
Cell growth/proliferation
Cell migration
Cell morphology
Cell viability/toxicity
Co-localization
Confluency
Cytotoxicity
Histology
Immunofluorescence
NF-κB translocation
Organoid/spheroid morphology
Transfection efficiency

Resources

Application Notes

Counting adherent cells in multi-well plates with the CELENA X
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Non-destructive quantification of cytotoxicity in live HeLa cells using the CELENA X
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Wound healing analysis based on image segmentation
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Downloads

Objective Selection Guide
DOWNLOAD
LED Filter Cube Selection Guide
DOWNLOAD

Supplier

Logos Biosystems, Inc.

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Measure mitochondrial respiration and glycolysis as well as ATP production rate of live cells.

Measure mitochondrial respiration, glycolysis, and ATP production in live cells in a 96-well format

Overview of Consumables for XF Analyzers

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High multiplexing, high resolution in situ platform to combine single-cell and spatial genomics.

The best super-resolution microscopy experience, on your desktop.

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The NovoCyte Penteon™ is a 5 laser benchtop flow cytometer with up to 30 colors

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An incubator designed specifically for the cultivation of primary human cells

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Automated high content image acquisition and analysis for drug discovery and cell biology

Multicolor fluorescence imaging to data analysis in one device

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Sterile, easy-to-use solutions for high cell integrity of single cell dispensing

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DeepLabel™ Antibody Staining Kit for Cleared Tissues

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Kits and reagents for real-time fluorescence plate reader-based live cell metabolism assays

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The best value benchtop flow cytometer with high flexibility, enhanced sensitivity and resolution.

Optimized solution for assessing mitochondrial function.

Provides real-time measurements of glycolysis

Measures human (Hu) T cell activation response within several minutes of stimulation

Formulated media based on common culture media DMEM or RPMI, and optimized for use in XF assays.

Analytical method for measuring basal state mitochondrial fuel oxidation in live cells

Identification of drug-induced mitochondrial toxicity

Provides validated reagents to measure long chain fatty acid oxidation (FAO)

For in vitro studies of long chain fatty acid oxidation by intact cells.

Permeabilizes intact cells in culture, selectively targeting the cellular plasma membrane.

Seahorse XF Real-Time ATP Rate Assay

A suite of optimized solutions for rapidly measuring cellular substrate oxidation

Robust & accurate measurements of both glycolytic and mitochondrial activities in T cell populations

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