Mission Bio Tapestri®
Untangle the complexity of cancer with true multi-omics.
The Tapestri Platform is the only system capable of simultaneously providing both genotype and phenotype data from the same cell, across thousands of single cells. With DNA as a foundation, our proprietary two-step microfluidic workflow enables the simultaneous detection of analytes, including SNVs, CNVs, and proteins. Meet the complexity of cancer with true multi-omics analysis.
Gain the true single-cell picture to enable precise understanding
Precise and Powerful
- High throughput: Up to 10,000 cells
- Multi-omic SNV, indel, CNV and protein data from the same single cell
- Detect rare subclones down to 0.1%
- Identify mutation co-occurrence and zygosity
- Small footprint of one square foot
Evolving subclonal mutations can resist and escape treatment
The industry’s first scalable, customizable, single-cell DNA analysis platform.
The Mission Bio Tapestri Platform was developed to help advance precision medicine by enabling the accelerated and accessible detection of genomic variability within and across cell populations. Leveraging proprietary droplet microfluidics, the platform unlocks access to DNA at the single-cell level with a novel two-step protease workflow. This methodology provides flexibility for additional applications and customization capability.
Break Out of the Limitations of Bulk.
The average read-out from conventional bulk sequencing misses the underlying genetic diversity across cell populations. To improve patient stratification, therapy selection, and disease monitoring we need insights into mutation co-occurrence within every single cell.
Genome Editing
Advances in genome editing have transformed our ability to deliver precision therapies by engineering specific sequence edits in almost any cell in any genome. While powerful, these genome edits are not always accurate or efficient, and precision tools are needed to provide quality control in ensuring the appropriate edits have been incorporated. Tapestri Single-Cell Custom DNA Panels provides single-cell resolution to assess targeting efficiency of genome editing constructs.
Learn moreIndels
Because bulk misses the diversity that matters.
The average read-out from conventional bulk sequencing misses the rare events and underlying genetic diversity within and across cell populations. The Tapestri Platform is the first and only single-cell platform to simultaneously detect Copy Number Variants (CNVs) and Single Nucelotide Variants (SNVs) from the same cells. To resolve heterogeneity and improve patient stratification, therapy selection, and disease monitoring we need to detect rare clonal populations and identify co-occurrence and zygosity within every single cell.
Learn moreCNVs
Because the change in our blueprint is where cancer begins.
The only single-cell targeted DNA solution that provides both copy number variants (CNVs) and single nucleotide variants (SNVs) from the same cell. Characterize genomic heterogeneity using a single platform, with comprehensive single-cell DNA analysis to co-detect both SNVs and CNVs.
Learn MorePhenotpye
Because the complexity of cancer needs both.
Introducing the first and only single-cell multi-omic platform capable of detecting SNVs, CNVs, and protein changes simultaneously from the same cell. Gain a true multi-omic picture from genotype to phenotype for your critical cancer research.
Learn MoreVideos
News & Testimonials
- Catherine Smith, MD, UCSF (Helen Diller Family Comprehensive Cancer Center)
"No technology prior to Tapestri has been able to give us the resolution to decipher co-occurring mutations in the same clones."
"These insights are especially important in our study of resistance mechanisms and combinatorial therapies in key clinical trials."
Koichi Takahashi, MD – The University of Texas (MD Anderson Cancer Center)
"This new capability of single-cell analysis is critical to better understanding precision therapy selection at diagnosis as well as disease monitoring and subsequent treatment strategy.”
Resources
Download
Supplier
Mission Bio
Request a demo or a quote
Thank you for contacting us!
{{ successMessage }}